Consumption of green tea protects rats from exercise-induced oxidative stress in kidney and liver
Author: Helaine M Alessio and Ann E Hagerman and Mary Romanello and Stephane Carando and Melinda S Threlkeld and J Rogers and Yoana Dimitrova and Subiquah Muhammed and Ronald L Wiley
The effects of green tea on biomarkers of exercise-induced oxidative status were measured in young male Sprague-Dawley rats. Rats (n = 12) drank green tea or water ad lib for 6.5 weeks. Half of each group was sacrificed at rest, and the other half ran 25 m/min at 0% grade for approximately 30 min immediately before sacrifice. Green tea had no effect on resting heart rate, blood pressure, body weight, cholesterol, or triglycerides. Tea consumption had a mild influence on total plasma antioxidants, heart glutathione, and plasma ascorbic acid. Exercise had a major impact on malonaldehyde (MDA) equivalents in kidney (+290%, p = 0.0001), and to a lesser extent, liver (+81%, p = 0.18) in rats that drank water. In contrast, kidney MDA equivalents were unchanged by exercise in rats that drank green tea. Green tea may have selective protective effects within the body, especially on the kidney.