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Synthesis of phosphates and phosphates–acetates hybrids of green tea polyphenol (−)-epigallocatechine-3-gallate (EGCG) and its G ring deoxy analogs as potential anticancer prodrugs

Synthesis of phosphates and phosphates–acetates hybrids of green tea polyphenol (−)-epigallocatechine-3-gallate (EGCG) and its G ring deoxy analogs as potential anticancer prodrugs

Author: Congde Huo and Q. Ping Dou and Tak Hang Chan

A series of phosphate or phosphate–acetate hybrid modified EGCG or EGCG G ring deoxy analogs were synthesized by a convenient semi-synthesis strategy from the abundant natural compound EGCG.

 

 

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